Cannabis / Hemp Isolation
When a cannabinoid is isolated, it is in its purest form. Isolation is often associated with the cannabinoid CBD and other minor cannabinoids.
DUAL-JACKETED 316L-GRADE STAINLESS STEEL REACTOR
The SR100 and SR200 316L stainless steel reactors from Across International are a great choice for a variety of processing applications such as decarboxylation, crystallization, or winterization.
Each reactor is available with an electric or pneumatic stirring motor, and they include a fluid jacket for temperature control as well as a vacuum jacket for insulation. They also include a high-surface-area tube and a shell heat exchanger.
100L or 200L
Electric or Pneumatic
CASCADE FILTER REACTOR PACKAGE
Cascade Sciences’ Filter Reactor Packages are available in 20L and 50L sizes. They are an all-in-one filter reactor package for isolate production.
The adjustable height and maximum stir bar coverage allow for maximum isolate yield.
20L or 50L
Vacuum Pump & Temperature Control
HEINKEL COMBER CONDRY BOTTOM-AGITATED CONICAL DRYER
The Condry is a bottom-agitated conical vacuum dryer from Heinkel.
The agitator provides uniform mixing of the material inserted without forming lumps or balls, thus eliminating having to chop up the material to aid in the drying process.
Continuous Conical Vacuum Dryer
cGMP & FDA
Isolation in cannabis processing usually refers to the isolation of the cannabinoid CBD. When isolated, CBD becomes a 99% pure, white powder that can then be used for a variety of medicinal and pharmaceutical applications.
CBD “isolate” as it is commonly known, is a highly purified substance that makes dosing quite simple, as there are no other cannabinoids that need to be accounted for in the mixture.
Isolation of other cannabinoids is also possible. Another cannabinoid that is often isolated in a similar manner to CBD, is CBG. CBG isolate has a very similar appearance to CBD but has some different medicinal properties that may be more useful than CBD isolate. Overall, almost any cannabinoid can be isolated to a high-purity form, although it is difficult to stabilize many of the cannabinoid isomers.
How to Make CBD Isolate
CBD isolate requires crude oil that already has high CBD content. This crude oil must be fully winterized, and have all contaminants and unwanted compounds fully removed. Once this is done, the crude oil must be distilled to create high potency CBD distillate. This CBD distillate is then used for the main isolation procedure.
To fully isolate CBD, a crystallization procedure must be performed on the CBD distillate. This entails using a solvent to saturate the CBD distillate. This super-saturated mixture is heated and stirred and then allowed to cool. The change in temperature and agitation forces nucleation of the cannabinoids and begins to crystallize the CBD in the mixture.
The excess solvent and non-crystallized cannabinoid mix (known as mother liquor) is drained and the process is repeated until all non-CBD cannabinoids are shed from the crystalline structure. The final product is a 99% pure, white powder known as CBD isolate.
Isolate is a highly sought-after end product due to its high purity. Isolate makes dosing very simple and allows for a pure pharmaceutical-grade end product. Isolation of cannabinoids can take many forms but they all refer to the isolation of one specific cannabinoid to create a 99% pure compound. Isolation is very dependent on the pre-processing steps which create a clean, highly potent oil or distillate to use in the isolation process.
We carry all the equipment necessary to perform this important step in the process. And we have years of expertise setting up labs in all phases of cannabis (post)processing.
Please contact us for more information on isolation systems and proper sizing for your facility.